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Philadelphia 76ers vs Los Angeles Clippers Odds, Spread, and Totals

The Philadelphia 76ers will take a cross-country trip to visit the Los Angeles Clippers at 10 p.m. EST on Monday. Both teams have realized success recently, with the Sixers rattling…

PHILADELPHIA, PENNSYLVANIA - NOVEMBER 17: VJ Edgecombe #77 of the Philadelphia 76ers drives to the basket against Kobe Sanders #4 of the LA Clippers during the second half of a game at Xfinity Mobile Arena on November 17, 2025 in Philadelphia, Pennsylvania. NOTE TO USER: User expressly acknowledges and agrees that, by downloading and or using this photograph, User is consenting to the terms and conditions of the Getty Images License Agreement. (Photo by Emilee Chinn/Getty Images)
Emilee Chinn/Getty Images

The Philadelphia 76ers will take a cross-country trip to visit the Los Angeles Clippers at 10 p.m. EST on Monday. Both teams have realized success recently, with the Sixers rattling off three straight wins, while the Clippers have taken home victories in four of their last five contests. Something has to give in Monday night's contest, which should make it a good one. 

While Philly has been playing well recently, its quality of competition, or lack thereof, must be noted. Its two most recent victories came against the New Orleans Pelicans and the Sacramento Kings, the two worst teams in the Western Conference. The three-game win streak kicked off with a win against the Milwaukee Bucks, who were playing without Giannis Antetokounmpo. The Clippers, despite their losing record, are a serious step up in competition for a team that has consistently struggled against quality opponents.

Los Angeles has also scored some easy wins lately, but wins against the Phoenix Suns and the Los Angeles Lakers show that the Clippers have what it takes to measure up to just about any team in the NBA. However, this game is the second leg of a back-to-back, which will inevitably call the status of forward Kawhi Leonard into question. Guard James Harden also missed Sunday's game due to a personal matter, leaving his status for Monday up in the air. Los Angeles is playing well, but the Sixers will be a stiff test given the circumstances.

Spread

  • 76ers +2.5 (-113)
  • Clippers -2.5 (+104)

Money line

  • 76ers +117
  • Clippers -122

Totals

  • Over 220.5 (-104)
  • Under 220.5 (-104)

Note: The above data was collected on Feb. 2, 2026, and may have changed since writing.

  • The Sixers are 27-21 ATS this season.
  • The Sixers are 14-6 ATS when they play on the road.
  • The over is 25-23 in Philadelphia's games.
  • The Clippers are 7-9 ATS when they enter the game as a home favorite.
  • The Clippers are 3-4 ATS in the second leg of back-to-backs.
  • The under is 25-23 in Los Angeles's games.

76ers vs Clippers Injury Reports

Philadelphia 76ers

  • Joel Embiid, C - Probable.

Los Angeles Clippers

  • James Harden, G - Questionable.
  • Derrick Jones Jr., F - Out.

76ers vs Clippers Prediction and Pick

The line indicates that the books expect Leonard to take the floor, even though he is nearly certain to receive an injury designation on game day. Regardless, it is a bit surprising to see the Clippers as favorites. Playing without rest is a significant disadvantage, and Harden seems likely to miss this contest given that he was ruled out for a personal issue just the day before. Without one of their best overall players, Los Angeles will struggle to keep pace with a potent Sixers offense that has been firing on all cylinders in recent outings. The right bet is to take Philadelphia to cover in what should be a hotly contested game between playoff-caliber teams. The over is also worth a look, especially if the injury reports on both sides stay relatively clean.