Philadelphia Phillies vs Los Angeles Dodgers Odds, Spread, and Totals

The Philadelphia Phillies will put their season on the line when they face the Los Angeles Dodgers on Wednesday night. Despite opening the series at home, the Phillies dropped both of the first two games, putting themselves in an intimidating hole as they prepare to travel to Los Angeles. The Dodgers have eked out back-to-back wins and now have the opportunity to sweep their second opponent in a row in front of their home fans.

The starting pitching rotation has been one of Philadelphia's strengths all season, but it will be forced to call upon one of the weaker arms in a season-defining moment. Aaron Nola, once one of the best pitchers in the MLB, endured a nightmarish regular season that was filled with injuries and downright bad play. In the 17 games Nola did manage to appear in, he accumulated a 6.01 ERA and a 1.35 WHIP. The fact that Los Angeles has been significantly worse against lefties does help Nola, but this should still be a difficult matchup.

The Dodgers have a much more reliable arm on the mound on Wednesday. Yoshinobu Yamamoto had an excellent regular season, earning a 2.49 ERA and a 0.99 WHIP over 30 starts. His lone postseason appearance so far was also strong, with the righty working through 6.2 innings of scoreless ball against the Cincinnati Reds. Philadelphia's bats, particularly at the top of the lineup, have been quiet, and Yamamoto has a good chance of keeping them that way on friendly turf.

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Note: The above data was collected on Oct. 8, 2025, and may have changed since writing.

Philadelphia Phillies

Los Angeles Dodgers

Kenny Ducey of Covers writes, "Yoshinobu Yamamoto is a trickier guy to figure out, surprisingly. Yes, his expected numbers and 29.4% strikeout rate glisten. He still ran a pedestrian 8.6% walk rate this season and issued three free passes to the Phillies to five strikeouts when he saw them in April. He owns a 2.84 ERA in his postseason career, but his 3.99 FIP tells the story of a man who's too often victimized by walks and homers.

Philly may not have hit all that well on the whole against ground-ball pitchers like Yamamoto, but it did slug .396 to rank ninth in baseball this season. It's going to need to recover in a big way here as it's struck out in 30.1% of its plate appearances in this series, but a 9.6% walk rate helps them here against Yamamoto. If Harrison Bader can return to the lineup ... this team should be able to do enough to pull this one out."