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Boston Red Sox vs Philadelphia Phillies Odds, Spread, and Totals

The Boston Red Sox will attempt to recover from a brutal series-opening loss to the Philadelphia Phillies in tonight’s rematch. Both teams received excellent performances from their pitching staffs, holding…

Cristopher Sánchez #61 of the Philadelphia Phillies delivers a pitch during a game.
Hunter Martin/Getty Images

The Boston Red Sox will attempt to recover from a brutal series-opening loss to the Philadelphia Phillies in tonight's rematch. Both teams received excellent performances from their pitching staffs, holding a 2-2 tie heading into extra innings before the Phillies managed to score the winning round in the tenth inning on an interference call. That loss marked the third defeat in Boston's last four games, making this an important rebound opportunity.

Leading the attempt to get back in the win column for the Red Sox is starting pitcher Richard Fitts. The young righty has only made eight starts this season, putting up a 4.28 ERA and a 1.22 WHIP. Those numbers are solid, but there is some concern about the rust Fitts might have accrued since his last appearance, given that he has not pitched since early July. A good Philadelphia lineup is not an ideal matchup for a young starter who will attempt to get back in the flow of things, but Fitts will have to make do tonight.

Unsurprisingly, the Phillies once again have the pitching advantage, this time thanks to Cristopher Sanchez. Sanchez has effectively rounded out one of the best rotations in the MLB, posting a 2.50 ERA and a 1.14 WHIP in 19 appearances this season. If his recent history is any indication, the Red Sox are in for a long night, as Sanchez has put up three straight performances in which he held the opposition to one run over seven innings of work. A date with the struggling Sox could see a similar outing from Sanchez tonight.

Spread

  • Red Sox +1.5 (-123)
  • Phillies -1.5 (+111)

Moneyline

  • Red Sox +173
  • Phillies -192

Totals

  • Over 8.5 (-104)
  • Under 8.5 (-112)

*The above data was collected on July 22, 2025, and may have changed since writing.

  • The Red Sox are 29-21 ATS when playing on the road.
  • The Red Sox are 24-14 ATS when they enter the game as an underdog.
  • The under is 26-21 in games following a Boston loss.
  • The Phillies are 51-49 ATS this season.
  • The Phillies are 25-31 ATS following a win.
  • The over is 25-22-3 in Philadelphia's home games.

Red Sox vs Phillies Injury Reports

Boston Red Sox

  • Justin Slaten, RP - Out.

Philadelphia Phillies

  • Alec Bohm, 3B - Out.

Red Sox vs Phillies Predictions and Picks

Chris King of Winners and Whiners writes, "Boston was hot heading into the All-Star break before being stymied by the Cubs for most of the weekend. While the Red Sox did win Sunday, Fitts hasn't been overwhelming at any point this season, and having to square off with Sanchez is going to be a challenge. Sanchez has been stellar of late, allowing two runs or less in nine straight starts, including a single run in each of his last five outings. The Phillies have a solid lineup that is capable of putting up crooked numbers, even with their recent struggles. Look for Sanchez to hold the Red Sox in check while the bats carry the hosts to victory here."