Philadelphia Phillies vs Houston Astros Odds, Spread, and Totals
At this point in the season, clear playoff contenders have begun to separate themselves from the pack. Two such teams will face off in this game when the Philadelphia Phillies…
PHILADELPHIA, PENNSYLVANIA – JUNE 22: Edmundo Sosa #33 of the Philadelphia Phillies breaks his bat on an infield single in the bottom of the third inning against the New York Mets at Citizens Bank Park on June 22, 2025 in Philadelphia, Pennsylvania. The Phillies defeated the Mets 7-1. (Photo by Mitchell Leff/Getty Images)
At this point in the season, clear playoff contenders have begun to separate themselves from the pack. Two such teams will face off in this game when the Philadelphia Phillies take on the Houston Astros. Both teams lead their respective divisions, but neither owns a commanding lead, making this a hugely important litmus test for both squads.
Marking this meeting of two elite teams is an excellent pitching matchup. The Phillies will call upon Ranger Suarez here, a proposition that has consistently yielded good results for Philadelphia. The lefty is the proud owner of a 2.20 ERA and a 1.06 WHIP over his nine starts, quickly recovering from an injury that held him out of the early going and an awful first appearance of the season. Suarez faces one of his toughest matchups of his season against an Astros lineup that hits exceptionally well against left-handed pitching.
It is quite rare to see two high-level left-handed pitchers face off against one another, but that is the case in this matchup. Framber Valdez has been playing quality baseball since 2020, and 2025 has been an extension of that solid body of work. While his numbers are not quite as good as Suarez's, Valdez can be counted upon to deliver six or seven innings of two-run ball even against the best offenses in the MLB. The Phillies will surely test that standard here.
Spread
- Phillies +1.5 (-169)
- Astros -1.5 (+146)
Moneyline
- Phillies +130
- Astros -151
Totals
- Over 7 (-122)
- Under 7 (+103)
*The above data was collected on June 24, 2025, and may have changed since writing.
Phillies vs Astros Betting Trends
- The Phillies are 40-38 ATS this season.
- The Phillies are 21-17 ATS when playing on the road.
- The under is 23-14-1 when Philadelphia plays away from home.
- The Astros are 37-41 ATS this year.
- The Astros are 18-22 ATS when playing at home.
- The under is 14-7 when Houston plays a National League opponent.
Phillies vs Astros Injury Reports
Philadelphia Phillies
- Bryce Harper, 1B - Out
Houston Astros
- Jacob Melton, LF - Out
- Yordan Alvarez, DH - Out
- Chas McCormick, OF - Out
- Zach Dezenzo, INF - Out
- Brendan Rodgers, 2B - Out
Phillies vs Astros Predictions and Picks
James Boutros of Statsalt writes, "Ranger Suarez is expected to take the mound for the Phillies. On the season, he has a record of 6-1 in nine starts with a 2.20 ERA, 1.06 WHIP, 52/14 K/BB ratio, and opponents are hitting .221 against Suarez. Philadelphia has a good offense. They are top 10 in batting average, on-base %, runs, and slugging %. The Phillies will win this contest. Take Philadelphia on the money line."
The Phillies might eke out a win here, but their moneyline is not the best pick on the board. Instead, the over is the way to go. The Astros hit left-handed pitching well, and they should be able to put up a few runs on Suarez, despite his recent dominance. The Phillies sport similar statistics against lefties, making it somewhat likely that they can tag Valdez for a handful of runs. That, combined with the inevitable scoring runs that will occur against the bullpens, makes the over an obvious selection.
