Chicago Cubs vs Philadelphia Phillies Odds, Spread, and Totals
The Chicago Cubs will continue their series against the Philadelphia Phillies. The two playoff hopefuls split the first two contests of the series, with the Phillies surviving an extra-innings thriller…

PHILADELPHIA, PENNSYLVANIA – JUNE 10: Max Kepler #17 celebrates his two-run home run in the second inning with J.T. Realmuto #10 of the Chicago Cubs during a game against the Chicago Cubs at Citizens Bank Park on June 10, 2025 in Philadelphia, Pennsylvania. (Photo by Emilee Chinn/Getty Images)
The Chicago Cubs will continue their series against the Philadelphia Phillies. The two playoff hopefuls split the first two contests of the series, with the Phillies surviving an extra-innings thriller before Chicago evened the set at one apiece. The rubber match is next up in what has been a fantastic series of National League baseball.
An injury to ace Shota Imanaga has forced the Cubs to call upon some other arms to fill the void. Ben Brown has answered the call, providing 11 starts with less than satisfactory results. The righty has posted a 5.37 ERA and a 1.63 WHIP through his starts and two appearances out of Chicago's bullpen. Despite how poor those statistics look, Brown might be hitting his stride as he enters this game. In his last two outings, he held the Cincinnati Reds scoreless over six innings and limited the Detroit Tigers to two runs over seven frames. Another quality start against Philadelphia would officially put Brown on the rebound.
The Phillies do not exactly have a star on the mound in this game either. Jesus Luzardo is in the middle of his second straight subpar season, putting up a 4.46 ERA and a 1.44 WHIP over his 13 starts. Unlike Brown, his last two starts have been downright nightmarish, as the Toronto Blue Jays rocked him for eight runs over two innings. Prior to that, the Milwaukee Brewers hurt Luzardo even worse, dropping 12 runs in three innings of work. The Cubs are an excellent offensive team, so Philadelphia manager Rob Thomson has to be concerned heading into this contest.
Spread
- Cubs -1.5 (+151)
- Phillies +1.5 (-186)
Moneyline
- Cubs -101
- Phillies -111
Totals
- Over 8.5 (-115)
- Under 8.5 (+103)
*The above data was collected on June 11, 2025, and may have changed since writing.
Cubs vs Phillies Betting Trends
- The Cubs are 20-6 ATS in games following a defeat.
- The Cubs are 20-16 ATS when playing on the road.
- The over is 19-14-3 when Chicago plays away from home.
- The Phillies are 14-19 ATS when playing at Citizens Bank Park.
- The Phillies are 18-20 ATS in games following a victory.
- The over is 17-15-1 when Philadelphia plays at home.
Cubs vs Phillies Injury Reports
Chicago Cubs
- Miguel Amaya, C - Out
- Porter Hodge, RP - Out
Philadelphia Phillies
- Bryce Harper, 1B - Out
- Brandon Marsh, CF - Day-to-Day
Cubs vs Phillies Predictions and Picks
Chris King of Winners and Whiners writes, "This one will be interesting as the two starting pitchers in this contest have trended in opposite directions of late. Brown threw six scoreless frames, allowing one hit and fanning nine in a game the Cubs won over the Reds, where he came in after an opener. He followed that up with his quality start against the Tigers, even though he took the loss, as he squared off with reigning AL Cy Young winner Tarik Skubal. Meanwhile, Luzardo has been scorched in his last couple of starts, giving up 20 runs on 21 hits over his last 5.2 innings of work. His ERA more than doubled from 2.15 to 4.46 in that stretch. The Phillies are a good team, but they're in a bit of a slump. Until Luzardo rebounds, you have to fade him slightly. Look for the Cubs to prevail here on getaway day."